Colorado vs. Arizona – November 1, 2025 Showdown

The Colorado Buffaloes and the Arizona Wildcats are set to face off in a highly anticipated Big 12 matchup on November 1, 2025. This game in Boulder, Colorado, promises to be more than just another date on the schedule. It’s a meeting of two programs with very different recent histories, both looking to make a statement in their new conference home. In this detailed preview, we’ll explore the background of both teams, their current season highlights, key players to watch, any brewing rivalries, and what to expect when these teams clash on the field. The language will be simple and conversational – no dense sports jargon here – to ensure every reader can follow along and get excited for the game.

Background: Two Programs on Different Paths

Colorado Buffaloes: The Buffaloes have a proud football history, including a shared national championship in 1990, but recent decades have been a rollercoaster. In an effort to revive Colorado’s glory days, the university made a splash by hiring head coach Deion “Coach Prime” Sanders in late 2022. Sanders immediately brought new energy, national attention, and a swarm of talented players to Boulder. The 2023 season under Coach Prime was a rebuilding one filled with growing pains and flashes of excitement, but by 2024 the Buffaloes had transformed into a formidable squad. In their first year in the Big 12 Conference (after moving from the Pac-12), Colorado exceeded expectations – they even finished with a 7-2 conference record, tying for the best record in the league. Many observers called it Colorado’s best team in nearly a decade. Coach Sanders’ influence was evident in the talent on the roster; he continued to attract top recruits and transfers to Colorado, assembling multiple top-25 recruiting classes. For example, the 2025 class featured a five-star quarterback prospect and a top defensive lineman transfer from the SEC, underscoring how much new talent is flocking to Boulder. In short, Colorado comes into this matchup as a rejuvenated program, with Coach Prime’s bravado and belief energizing the fanbase.

Arizona Wildcats: The Wildcats, based in Tucson, Arizona, have historically been known as a gritty program still chasing that elusive first outright conference title in the modern era. Arizona’s peak moments include the “Desert Swarm” defense of the 1990s and a few 10-win seasons, but consistency has been hard to come by. Recently, Arizona enjoyed a resurgence in 2023 under head coach Jedd Fisch, even earning a bowl appearance and finishing with a strong record. However, the Wildcats experienced major change afterward – Coach Fisch departed the program (reportedly for another coaching opportunity), and Arizona brought in Brent Brennan as the new head coach for 2024. Brennan inherited a team that had been on the rise, but the transition proved challenging. In their first Big 12 season in 2024, the Wildcats struggled to maintain the previous year’s momentum and finished with a disappointing 4-8 record (2-7 in conference play). By the end of that season, Coach Brennan was openly taking responsibility for the team’s struggles, telling fans “we have a lot of work to do as a football team… it’s 100 percent my fault”. Arizona entered 2025 in rebuild mode, determined to turn things around. In this second year under Brennan (and second year in the Big 12), the Wildcats aimed to avenge the previous season’s difficulties and power ahead with a fresh start. They retained some key talent despite the losing season, and with a full offseason in the new system, Arizona hoped to be a more competitive squad in 2025.

Both programs also share the experience of conference realignment. This game marks the second year that Colorado and Arizona are conference foes in the Big 12 after leaving the Pac-12. That backdrop gives the matchup an extra layer of intrigue: these teams are forging new identities in a new league, and every conference game is a chance to prove they belong at the top.

Season Highlights So Far in 2025

By the time November 1 rolls around, both teams will have a half-season of 2025 games under their belts. Let’s recap how each team’s season has been going up to this point:

Colorado’s 2025 Season: The Buffaloes entered 2025 with high expectations thanks to their strong 2024 campaign. So far, they have shown that last year was no fluke. Colorado kicked off the season with an exciting non-conference slate, including a game against Georgia Tech that rekindled memories of the disputed 1990 title (the two schools split the national championship that year). From there, the Buffs handled business against teams like Delaware and Wyoming, games that helped them build confidence and work out any kinks early in the season. Once conference play began, Coach Sanders’ squad continued to impress. A key early Big 12 matchup saw Colorado travel to TCU, where they famously upset the Horned Frogs in 2023; in 2025, the Buffs proved it wasn’t a one-time thing by delivering another solid performance on the road in Fort Worth. By mid-season, Colorado was once again in the mix at the top of the Big 12 standings, showing a potent offense and a much-improved defense. One hiccup came in an away game at Utah on October 25 – a hard-fought contest against a tough rival that tested Colorado’s resilience. Whether they won or lost that Utah game, it surely prepared the Buffs for the intensity of late-season football. Coming into the Arizona game, Colorado’s record is strong and they’ve hit a stride, looking every bit like a contender. Notably, the Buffs have shown they love playing at home in Boulder: Folsom Field’s crowd and the altitude give them a nice advantage, and they’ll have that on their side come November 1.
Arizona’s 2025 Season: For the Wildcats, 2025 has been about steady improvement. They started the season trying to put 2024 behind them. In Week 1, Arizona hosted Hawai’i and opened with a win in Tucson, which was an important confidence booster. They followed that with another home victory against FCS opponent Weber State. These early wins matched the team’s entire home win total from the previous year, signaling progress. However, the schedule grew more challenging as Arizona hit Big 12 play. A Week 3 showdown against Kansas State was highlighted in the schedule as a measuring stick – Arizona had lost to K-State the year before, starting a long skid. This time around, Arizona put up a better fight, showing flashes of the offensive firepower that fans remembered from 2023. Quarterback Noah Fifita and his receivers tested a tough K-State defense, and while Arizona may not have come out on top, there were positives to build on. In subsequent weeks, the Wildcats faced a mix of new and old foes: a trip to Iowa State (an old opponent they hadn’t seen since the 1960s), a home game against Oklahoma State, and a meeting with BYU – a team Arizona has a long history with from their days together in the Western Athletic Conference. Arizona had ups and downs through this stretch. By late October, they secured a gritty road win at Houston, which was significant as it snapped a road losing streak and came right before their bye week. Indeed, Arizona had a bye week on October 25, meaning they get a week of rest and extra preparation leading into the Colorado game. This could be a crucial advantage for the Wildcats – they’ll arrive in Boulder a little fresher, with extra time to game-plan for Coach Prime’s Buffs. Overall, while Arizona’s 2025 record ahead of this game might still be around the .500 mark, the team’s trajectory is upward. They’ve been more competitive than last year and have shown they can put points on the board when things click.

In summary, Colorado comes in as a team building on strong performances and perhaps eyeing a Big 12 title shot, whereas Arizona enters as a scrappy underdog looking to surprise people and continue climbing out of last year’s hole. These storylines set the stage for an intriguing contest.

A Budding Big 12 Rivalry and Recent History

When it comes to rivalry, Colorado and Arizona aren’t traditional arch-rivals – there’s no trophy on the line and no century-old grudge specific to these two. However, that doesn’t mean there’s a lack of history or intensity. In fact, this 2025 matchup will be the 28th all-time meeting between the Buffaloes and Wildcats. The series dates all the way back to 1931, when they faced each other for the first time. In those early days, Colorado absolutely dominated – Arizona lost the first 12 games in the series, unable to crack the code against the Buffs for over fifty years. That long early losing streak (from 1931 into the 1980s) is a quirky historical footnote that Wildcats fans would rather forget.

Fast forward to recent times, and the dynamic between these programs shifted once they became conference peers. From 2011 onward, when Colorado joined what was then the Pac-12, the Buffaloes and Wildcats played each other every season. Arizona began to get the upper hand for a while. During their Pac-12 years facing Colorado, Arizona won the majority of those meetings – the Wildcats often found ways to outscore Colorado in shootouts or capitalize on the Buffs’ struggles in the 2010s. In fact, going into the 2024 season Arizona had won two out of the three previous games against Colorado. This included thrilling contests like a 34-31 Arizona victory in 2023, where Arizona kicked a game-winning field goal as time expired in Boulder. Those kinds of games made it clear that while not a traditional rivalry, these teams can produce drama when matched up.

Then came last season’s game in 2024, which might serve as motivation for both sides in 2025. On October 19, 2024, Colorado traveled to Tucson and thumped Arizona 34-7 on Arizona’s Homecoming. It was a statement win for the Buffaloes and a humbling loss for the Wildcats. Colorado was firing on all cylinders that day: they jumped out to a 28-7 halftime lead and never looked back. The Buffs offense had its best rushing performance of the entire 2024 season in that game, racking up 148 yards and two touchdowns on the ground. Quarterback Shedeur Sanders (Coach Prime’s son) was efficient as well – he threw for 250 yards and tossed two touchdown passes, one to receiver Will Sheppard and another to freshman wideout Drelon Miller. On the other side of the ball, Colorado’s defense dominated Arizona’s offense. The Buffs’ pass rush was relentless, sacking Arizona quarterback Noah Fifita seven times over the course of the game. Arizona tried a bit of trickery to swing momentum – in a bold move, Coach Brennan opened the game with an onside kick attempt to catch Colorado off guard. It didn’t work. Colorado recovered the onside kick (which gave them great field position to start), and Coach Sanders later called that surprise kick “kind of disrespectful”, as if Arizona was assuming the Buffs wouldn’t be prepared. Clearly, Colorado was prepared. They made Arizona pay for the gamble, scoring a touchdown just a few plays later. By the second half of that game, Colorado was confident enough to pull some starters and coast, while Arizona’s players and fans were left stunned.

In the aftermath of the 34-7 game, there was a somber mood on the Arizona side. Head coach Brent Brennan apologized to the fans for the poor showing, as mentioned earlier, and admitted the team had a long way to go. Quarterback Noah Fifita, a young leader on the team, expressed the locker room’s disappointment. “We have a standard and we’re not living up to it. We’re extremely disappointed, but the only thing we can do is get back to work,” Fifita said after that loss. That quote captures Arizona’s mindset: they know they fell short of expectations and they’re determined to improve. For Colorado, that big win in Tucson was one of the highlights of their 2024 season, especially because it came on the road. It reinforced how far the Buffs had come under Coach Prime. In fact, by that point in 2024, some were saying that Colorado looked like its strongest self since at least 2016.

All these recent events add spice to the 2025 encounter. Arizona will surely be looking for redemption after the embarrassment of last year’s blowout. You can bet Coach Brennan has reminded his players of that feeling and is using it as fuel. Meanwhile, Colorado will be eager to show that last year’s result was no fluke – they want to prove they still have the upper hand and can handle Arizona again, this time in front of their home crowd. While Colorado vs. Arizona may not have the notoriety of Colorado vs. Nebraska or Arizona vs. Arizona State, it is developing into a competitive yearly battle. With both teams now firmly in the Big 12, there’s potential for a new rivalry to blossom, born out of these hard-fought games and contrasting program personalities.

The all-time series stands in Colorado’s favor at 17 wins for the Buffaloes and 10 wins for the Wildcats. Arizona would love to chip away at that gap, and a road win in Boulder would be a memorable way to do it. On the flip side, Colorado hopes to continue its recent series dominance. This context of past meetings and recent results sets the scene: there’s history, a touch of bad blood from last year, and plenty of motivation on both sidelines.

Key Players to Watch

When the Buffaloes and Wildcats take the field on November 1, many talented players will be in action. Here we highlight some key players from each team who could play pivotal roles in the outcome. These are the names to listen for and the storylines to know:

Colorado Buffaloes – Key Players

Kaidon Salter, QB: With last year’s star quarterback Shedeur Sanders no longer at Colorado (he moved on after the 2024 season), the Buffaloes turned to junior transfer Kaidon Salter to lead the offense. Salter came to Colorado from Liberty University and brought a dual-threat skill set – he’s capable of making plays with both his arm and legs. Coach Sanders was excited about Salter’s potential, and Salter has so far managed the offense well. He isn’t trying to be Shedeur; instead, he provides his own style, extending plays when protection breaks down and keeping defenses honest with his scrambling ability. By mid-season, Salter had grown more comfortable in Colorado’s up-tempo, spread offense, showing good chemistry with his receivers. His performance in this game will be crucial. If Salter can distribute the ball effectively and avoid turnovers, Colorado’s offense should hum. It’s worth noting that behind Salter is a very talented true freshman, Julian Lewis, a prized five-star recruit. While Lewis has mostly been waiting in the wings, the buzz around him is huge. Coach Prime might not hesitate to sprinkle the youngster in for a package of plays or be ready if needed. Still, expect Salter to be the primary signal-caller, and his play could decide if Colorado’s offense continues its high-scoring ways.
Micah Welch, RB: In 2024, the Buffaloes’ running game was sometimes overshadowed by their passing, but Micah Welch emerged as a bright spot out of the backfield. As a true freshman last year, Welch led the team in rushing and even had his best game against Arizona, where Colorado as a team ran for 148 yards. Now a sophomore, Welch has become the feature running back for Colorado. He’s a shifty runner with quick acceleration, capable of turning small openings into big gains. Welch’s ability to keep the offense balanced is important – when he’s running well, opposing defenses can’t just focus on the pass. Watch for Welch not only on traditional handoffs but also catching screen passes or swing passes; Colorado likes to get him in space to utilize his speed. Given that Arizona struggled to contain him last year, Welch will be licking his chops for another opportunity to gash the Wildcats on the ground.
Drelon Miller, WR: Among Colorado’s many receiving targets, Drelon Miller stands out as an exciting playmaker. Miller was one of Coach Prime’s highly rated recruits, and he wasted no time making an impact. As a freshman in 2024 he earned a starting role, and he even caught a touchdown in the win over Arizona. Miller is a speedy receiver with sharp route-running skills. At about 6 feet tall, he has a knack for getting separation downfield and is not afraid to go across the middle for tough catches. Now in his sophomore season, Miller has grown more polished and has become one of Colorado’s top receiving threats. The Buffs’ offense spreads the ball around – other notable targets include senior wideout Montana Lemonious-Craig (a reliable veteran with good hands) and transfer tight end Seydou Traore – but Miller’s big-play ability makes him a potential X-factor. If Arizona’s secondary can’t keep track of him, Miller could break loose for a long touchdown or two. Keep an eye on his matchup with Arizona’s cornerbacks; his speed versus their coverage will be a key battle.
Jordan Seaton, OT: Games are often won in the trenches, and for Colorado, left tackle Jordan Seaton is a name to know. Seaton was a five-star recruit (one of the highest-rated offensive linemen Coach Prime has ever signed) and he showed why as a true freshman in 2024, starting on the offensive line. Now as a sophomore, Seaton protects the quarterback’s blind side. His job in this game will be to neutralize Arizona’s pass rush and pave the way for the run game. Seaton is athletic and strong for a young lineman, and he’s part of an improved Colorado offensive line that has reduced the sacks allowed compared to the past. If you notice Colorado’s quarterback having plenty of time to throw or big holes opening for Welch, that likely means Seaton and his linemates are winning their battles up front.
Carter Stoutmire, CB: On defense, Colorado’s strength lies in an aggressive secondary, even after the departure of two-way star Travis Hunter to the NFL. One key defensive back is Carter Stoutmire, a junior cornerback. Stoutmire, along with fellow corners Dominique* (DJ) *McKinney and Colton Hood, form a unit that isn’t shy about man-to-man coverage. Coach Sanders, a Hall-of-Fame cornerback himself, has instilled a lot of confidence in this secondary. Stoutmire in particular has a reputation as a lockdown corner who can go one-on-one with top receivers. He had a couple of interceptions in 2024 and has continued that ball-hawking trend in 2025. Colorado’s defensive game plan often leaves players like Stoutmire “on an island” in single coverage while safeties help against the run or blitz. It’s a high-risk, high-reward style, but so far it’s worked – the Buffs lead the Big 12 in interceptions this season. In this game, Stoutmire will likely be tasked with covering Arizona’s best wideout. If he can blanket his man and perhaps snare an interception or deflect some passes, it will go a long way in stopping Arizona’s passing attack.
Taje McCoy, Edge Rusher: Another Colorado defender to watch is Taje McCoy, a sophomore edge rusher who has been coming into his own. McCoy contributed as a freshman and had some highlight plays (sacks and forced fumbles) in 2024. He’s now one of the Buffs’ primary pass rushers. McCoy has a quick first step and uses his leverage well to get past offensive tackles. In last year’s matchup, Colorado’s defense sacked Noah Fifita seven times – that kind of pressure disrupted Arizona’s offense completely. McCoy, along with other rushers like Derrick McLendon II (a seasoned transfer) and Arden Walker, will be looking to repeat that feat. His duel with Arizona’s offensive tackles is something to keep an eye on; if McCoy spends a lot of time in the Wildcats’ backfield, it will be a long day for Arizona. Conversely, if Arizona manages to keep him blocked, Fifita might have time to make some plays downfield. McCoy’s effectiveness off the edge could tilt the balance.

Arizona Wildcats – Key Players

Noah Fifita, QB: The engine of Arizona’s offense is Noah Fifita, the sophomore (perhaps now junior by eligibility) quarterback. Fifita is a compelling story – he’s not the prototypical tall QB (he’s around 5-foot-9 or 5-foot-10), but he plays with heart and has a strong arm. As a redshirt freshman in 2023, Fifita got his chance to play and impressed everyone by leading Arizona to some big wins and near-upsets. He solidified himself as the starting QB entering 2024. Though the 2024 season was rough for the team, Fifita gained invaluable experience going up against tough defenses week after week. He’s a mobile quarterback, able to evade rushers, which he had to do often (given that Arizona’s offensive line allowed quite a few sacks last year). Fifita’s strengths include quick decision-making and accuracy on short to intermediate throws. He is also known for keeping a cool head; even after losses, he remained poised and focused on improvement. He showed leadership beyond his years by publicly stating that the team wasn’t meeting its own standard and that they had to get back to work. Coming into this game, Fifita will be key to Arizona’s hopes. He’ll need to use his mobility to escape Colorado’s pass rush and perhaps tuck the ball and run for a first down here or there. Watch for designed roll-outs or bootleg plays to get Fifita moving and away from pressure. How he handles Colorado’s blitzes and disguised coverages will largely determine if Arizona can sustain drives. If Fifita can play a clean game (avoid interceptions) and maybe even improvise some off-schedule plays, the Wildcats’ offense becomes much more dangerous.
Jonah Coleman, RB: In the backfield for Arizona, Jonah Coleman is a name to know. Coleman is a junior running back who took on a bigger role after veteran backs like Michael Wiley graduated. He’s a compact runner, known for his low center of gravity and power. Coleman has been the workhorse for Arizona this season, grinding out tough yards and helping the Wildcats control the clock when they can. His stats won’t always wow you, but he has a habit of finding creases and falling forward for extra yards, turning what looks like a small gain into a solid 5 or 6 yards. Arizona’s offense works best when Coleman is effective, because it sets up manageable third downs for Fifita and opens up play-action passes. Coleman also contributes as a receiver on check-downs, showing good hands out of the backfield. Given Colorado’s aggressive defense, one way to counter it is running draw plays or screens with Coleman to exploit any over-pursuit. Keep an eye on Coleman’s workload; if he’s able to get 20+ carries in this game, it likely means Arizona is executing their game plan of a balanced attack. Also look for a change-of-pace back like DJ Williams or newcomer Quali Conley (a transfer who has shown bursts of speed) to spell Coleman – the Wildcats will try to keep the running game going to avoid becoming one-dimensional.
Tetairoa McMillan, WR: Arizona’s receiving corps is led by Tetairoa “T-Mac” McMillan – one of the most talented wide receivers the program has seen in years. McMillan is a junior with NFL potential, standing at 6-foot-4 with a wide catch radius. He was a star in 2023 (catching passes alongside teammate Jacob Cowing) and continued to be the go-to receiver in 2024. There was speculation he might go pro, but if you’re seeing him on the field in 2025, it’s a huge boost for Arizona. T-Mac is the kind of player who can make a quarterback’s life easier: he outleaps defenders for high throws, and he’s deceptively fast on deep routes. He’s also an excellent red zone target. In this game, McMillan’s matchup against Colorado’s secondary will be one of the marquee battles. Don’t be surprised if Colorado’s top corner (like Carter Stoutmire) is shadowing him all game. Fifita will likely look McMillan’s way often, especially on third downs or when Arizona needs a big play. Even if Colorado’s coverage is tight, McMillan has shown he can come down with contested catches. For Arizona to pull off a win, they may need a highlight-reel performance from T-Mac – think something like 100+ yards and a touchdown. If Colorado double-teams him, that could open opportunities for other receivers such as Kevin Green II or tight end Tanner McLachlan to make an impact. But make no mistake, McMillan is the star of this receiving group and a player to watch closely.
Jacob Manu, LB: On defense, Arizona’s leader is arguably Jacob Manu, a junior linebacker. Manu might not be a household name nationally, but Wildcats fans know him as the heart of their defense. Despite not being the biggest linebacker (around 5-foot-11, 225 pounds), Manu is a tackling machine and has great instincts. He led the team in tackles in both 2023 and 2024, flying sideline to sideline to stop ball carriers. Manu’s strength is diagnosing plays quickly – he’s often the first to react to a run play and fill the gap, or to sniff out a screen pass. In this matchup, Manu’s responsibilities will be huge. He’ll be tasked with spying on Colorado’s running back and quarterback; if Salter breaks the pocket, Manu might be the one coming up to contain him. Manu will also drop into coverage at times, where he’ll have to keep an eye on Colorado’s tight ends or running backs on short routes. Given Colorado’s balanced attack, Manu’s versatility will be tested. Look for number 7 (Manu’s jersey) around the ball – if Arizona’s defense is getting stops, it’s a good bet Manu is involved in the tackle. His leadership and communication will also be vital in ensuring Arizona is lined up properly against Colorado’s fast-paced offense.
Dalton Johnson, S: The Wildcats’ secondary has a standout in Dalton Johnson, a senior safety who has taken on a leadership role. Johnson was one of the players who spoke to the media after the tough loss to Colorado last year, showing his willingness to lead and be accountable. On the field, Dalton Johnson is known for being a hard hitter and an intelligent last line of defense. He often helps get the secondary lined up and will adjust coverages if he sees something. Johnson has also shown a knack for making timely plays – whether it’s an interception, a tipped pass, or a big third-down tackle to force a punt. In the 2025 season, he’s been the stabilizing force for an Arizona defense that has had its ups and downs. His matchup against Colorado will involve a lot of multitasking: sometimes he’ll play deep to prevent the long bomb, other times he’ll creep into the box to help stop the run or blitz. Johnson will need to keep the defense organized, especially against any trickery Colorado might try (Coach Sanders is not afraid to dial up creative plays). One particular challenge will be helping Arizona’s corners cover Colorado’s receivers in that aggressive style – he may have to assist over the top to ensure no Colorado receiver gets behind the defense. If Arizona is to contain Colorado’s offense, Dalton Johnson’s play at safety will be key. Keep an eye out for #1 in the secondary; his effectiveness in reading Colorado’s intentions could lead to a crucial turnover or a momentum-shifting defensive stand.
Taylor Upshaw, DL: In the trenches, a player to note is Taylor Upshaw, a defensive lineman who transferred into Arizona (interestingly, he’s a veteran who actually spent a short stint at Colorado before coming to Arizona). Upshaw provides experience and size up front. He’s been one of Arizona’s better pass rushers and run stoppers in 2025. At around 6-foot-4 and 270 pounds, Upshaw often lines up at defensive end but can move inside on passing downs. His motivation for this game might be extra high given his connection to Colorado’s program. Upshaw will try to generate pressure on Colorado’s quarterback and also set the edge to prevent runs to the outside. If he can win some one-on-one battles against Colorado’s offensive tackles (like the highly touted Jordan Seaton), that could stall the Buffs’ drives. Arizona as a team struggled to sack Colorado’s QB last year (unlike Colorado’s seven-sack performance), so Upshaw and fellow linemen like Orlando Lground or Bill Norton will be determined to change that narrative. Pressure without having to blitz will help Arizona’s defense immensely. Watch for Upshaw on key third downs – if he can flush Salter out of the pocket or bring him down for a sack, it could fire up the Wildcats defense and frustrate Colorado’s offense.

These players mentioned are just a few of the impact contributors. Football is the ultimate team game, so of course many other players will have roles – from special teams returners to role-playing receivers and nickel cornerbacks. But the ones listed above are likely to have their names called often during the broadcast. Their performances will heavily influence which way this game swings.

Key Players to Watch

Colorado Buffaloes – Key Players

Kaidon Salter, QB: With last year’s star quarterback Shedeur Sanders no longer at Colorado (he moved on after the 2024 season), the Buffaloes turned to junior transfer Kaidon Salter to lead the offense. Salter came to Colorado from Liberty University and brought a dual-threat skill set – he’s capable of making plays with both his arm and legs. Coach Sanders was excited about Salter’s potential, and Salter has so far managed the offense well. He isn’t trying to be Shedeur; instead, he provides his own style, extending plays when protection breaks down and keeping defenses honest with his scrambling ability. By mid-season, Salter had grown more comfortable in Colorado’s up-tempo, spread offense, showing good chemistry with his receivers. His performance in this game will be crucial. If Salter can distribute the ball effectively and avoid turnovers, Colorado’s offense should hum. It’s worth noting that behind Salter is a very talented true freshman, Julian Lewis, a prized five-star recruit. While Lewis has mostly been waiting in the wings, the buzz around him is huge. Coach Prime might not hesitate to sprinkle the youngster in for a package of plays or be ready if needed. Still, expect Salter to be the primary signal-caller, and his play could decide if Colorado’s offense continues its high-scoring ways.
Micah Welch, RB: In 2024, the Buffaloes’ running game was sometimes overshadowed by their passing, but Micah Welch emerged as a bright spot out of the backfield. As a true freshman last year, Welch led the team in rushing and even had his best game against Arizona, where Colorado as a team ran for 148 yards. Now a sophomore, Welch has become the feature running back for Colorado. He’s a shifty runner with quick acceleration, capable of turning small openings into big gains. Welch’s ability to keep the offense balanced is important – when he’s running well, opposing defenses can’t just focus on the pass. Watch for Welch not only on traditional handoffs but also catching screen passes or swing passes; Colorado likes to get him in space to utilize his speed. Given that Arizona struggled to contain him last year, Welch will be licking his chops for another opportunity to gash the Wildcats on the ground.
Drelon Miller, WR: Among Colorado’s many receiving targets, Drelon Miller stands out as an exciting playmaker. Miller was one of Coach Prime’s highly rated recruits, and he wasted no time making an impact. As a freshman in 2024 he earned a starting role, and he even caught a touchdown in the win over Arizona. Miller is a speedy receiver with sharp route-running skills. At about 6 feet tall, he has a knack for getting separation downfield and is not afraid to go across the middle for tough catches. Now in his sophomore season, Miller has grown more polished and has become one of Colorado’s top receiving threats. The Buffs’ offense spreads the ball around – other notable targets include senior wideout Montana Lemonious-Craig (a reliable veteran with good hands) and transfer tight end Seydou Traore – but Miller’s big-play ability makes him a potential X-factor. If Arizona’s secondary can’t keep track of him, Miller could break loose for a long touchdown or two. Keep an eye on his matchup with Arizona’s cornerbacks; his speed versus their coverage will be a key battle.
Jordan Seaton, OT: Games are often won in the trenches, and for Colorado, left tackle Jordan Seaton is a name to know. Seaton was a five-star recruit (one of the highest-rated offensive linemen Coach Prime has ever signed) and he showed why as a true freshman in 2024, starting on the offensive line. Now as a sophomore, Seaton protects the quarterback’s blind side. His job in this game will be to neutralize Arizona’s pass rush and pave the way for the run game. Seaton is athletic and strong for a young lineman, and he’s part of an improved Colorado offensive line that has reduced the sacks allowed compared to the past. If you notice Colorado’s quarterback having plenty of time to throw or big holes opening for Welch, that likely means Seaton and his linemates are winning their battles up front.
Carter Stoutmire, CB: On defense, Colorado’s strength lies in an aggressive secondary, even after the departure of two-way star Travis Hunter to the NFL. One key defensive back is Carter Stoutmire, a junior cornerback. Stoutmire, along with fellow corners Dominique* (DJ) *McKinney and Colton Hood, form a unit that isn’t shy about man-to-man coverage. Coach Sanders, a Hall-of-Fame cornerback himself, has instilled a lot of confidence in this secondary. Stoutmire in particular has a reputation as a lockdown corner who can go one-on-one with top receivers. He had a couple of interceptions in 2024 and has continued that ball-hawking trend in 2025. Colorado’s defensive game plan often leaves players like Stoutmire “on an island” in single coverage while safeties help against the run or blitz. It’s a high-risk, high-reward style, but so far it’s worked – the Buffs lead the Big 12 in interceptions this season. In this game, Stoutmire will likely be tasked with covering Arizona’s best wideout. If he can blanket his man and perhaps snare an interception or deflect some passes, it will go a long way in stopping Arizona’s passing attack.
Taje McCoy, Edge Rusher: Another Colorado defender to watch is Taje McCoy, a sophomore edge rusher who has been coming into his own. McCoy contributed as a freshman and had some highlight plays (sacks and forced fumbles) in 2024. He’s now one of the Buffs’ primary pass rushers. McCoy has a quick first step and uses his leverage well to get past offensive tackles. In last year’s matchup, Colorado’s defense sacked Noah Fifita seven times – that kind of pressure disrupted Arizona’s offense completely. McCoy, along with other rushers like Derrick McLendon II (a seasoned transfer) and Arden Walker, will be looking to repeat that feat. His duel with Arizona’s offensive tackles is something to keep an eye on; if McCoy spends a lot of time in the Wildcats’ backfield, it will be a long day for Arizona. Conversely, if Arizona manages to keep him blocked, Fifita might have time to make some plays downfield. McCoy’s effectiveness off the edge could tilt the balance.

Arizona Wildcats – Key Players

Noah Fifita, QB: The engine of Arizona’s offense is Noah Fifita, the sophomore (perhaps now junior by eligibility) quarterback. Fifita is a compelling story – he’s not the prototypical tall QB (he’s around 5-foot-9 or 5-foot-10), but he plays with heart and has a strong arm. As a redshirt freshman in 2023, Fifita got his chance to play and impressed everyone by leading Arizona to some big wins and near-upsets. He solidified himself as the starting QB entering 2024. Though the 2024 season was rough for the team, Fifita gained invaluable experience going up against tough defenses week after week. He’s a mobile quarterback, able to evade rushers, which he had to do often (given that Arizona’s offensive line allowed quite a few sacks last year). Fifita’s strengths include quick decision-making and accuracy on short to intermediate throws. He is also known for keeping a cool head; even after losses, he remained poised and focused on improvement. He showed leadership beyond his years by publicly stating that the team wasn’t meeting its own standard and that they had to get back to work. Coming into this game, Fifita will be key to Arizona’s hopes. He’ll need to use his mobility to escape Colorado’s pass rush and perhaps tuck the ball and run for a first down here or there. Watch for designed roll-outs or bootleg plays to get Fifita moving and away from pressure. How he handles Colorado’s blitzes and disguised coverages will largely determine if Arizona can sustain drives. If Fifita can play a clean game (avoid interceptions) and maybe even improvise some off-schedule plays, the Wildcats’ offense becomes much more dangerous.
Jonah Coleman, RB: In the backfield for Arizona, Jonah Coleman is a name to know. Coleman is a junior running back who took on a bigger role after veteran backs like Michael Wiley graduated. He’s a compact runner, known for his low center of gravity and power. Coleman has been the workhorse for Arizona this season, grinding out tough yards and helping the Wildcats control the clock when they can. His stats won’t always wow you, but he has a habit of finding creases and falling forward for extra yards, turning what looks like a small gain into a solid 5 or 6 yards. Arizona’s offense works best when Coleman is effective, because it sets up manageable third downs for Fifita and opens up play-action passes. Coleman also contributes as a receiver on check-downs, showing good hands out of the backfield. Given Colorado’s aggressive defense, one way to counter it is running draw plays or screens with Coleman to exploit any over-pursuit. Keep an eye on Coleman’s workload; if he’s able to get 20+ carries in this game, it likely means Arizona is executing their game plan of a balanced attack. Also look for a change-of-pace back like DJ Williams or newcomer Quali Conley (a transfer who has shown bursts of speed) to spell Coleman – the Wildcats will try to keep the running game going to avoid becoming one-dimensional.
Tetairoa McMillan, WR: Arizona’s receiving corps is led by Tetairoa “T-Mac” McMillan – one of the most talented wide receivers the program has seen in years. McMillan is a junior with NFL potential, standing at 6-foot-4 with a wide catch radius. He was a star in 2023 (catching passes alongside teammate Jacob Cowing) and continued to be the go-to receiver in 2024. There was speculation he might go pro, but if you’re seeing him on the field in 2025, it’s a huge boost for Arizona. T-Mac is the kind of player who can make a quarterback’s life easier: he outleaps defenders for high throws, and he’s deceptively fast on deep routes. He’s also an excellent red zone target. In this game, McMillan’s matchup against Colorado’s secondary will be one of the marquee battles. Don’t be surprised if Colorado’s top corner (like Carter Stoutmire) is shadowing him all game. Fifita will likely look McMillan’s way often, especially on third downs or when Arizona needs a big play. Even if Colorado’s coverage is tight, McMillan has shown he can come down with contested catches. For Arizona to pull off a win, they may need a highlight-reel performance from T-Mac – think something like 100+ yards and a touchdown. If Colorado double-teams him, that could open opportunities for other receivers such as Kevin Green II or tight end Tanner McLachlan to make an impact. But make no mistake, McMillan is the star of this receiving group and a player to watch closely.
Jacob Manu, LB: On defense, Arizona’s leader is arguably Jacob Manu, a junior linebacker. Manu might not be a household name nationally, but Wildcats fans know him as the heart of their defense. Despite not being the biggest linebacker (around 5-foot-11, 225 pounds), Manu is a tackling machine and has great instincts. He led the team in tackles in both 2023 and 2024, flying sideline to sideline to stop ball carriers. Manu’s strength is diagnosing plays quickly – he’s often the first to react to a run play and fill the gap, or to sniff out a screen pass. In this matchup, Manu’s responsibilities will be huge. He’ll be tasked with spying on Colorado’s running back and quarterback; if Salter breaks the pocket, Manu might be the one coming up to contain him. Manu will also drop into coverage at times, where he’ll have to keep an eye on Colorado’s tight ends or running backs on short routes. Given Colorado’s balanced attack, Manu’s versatility will be tested. Look for number 7 (Manu’s jersey) around the ball – if Arizona’s defense is getting stops, it’s a good bet Manu is involved in the tackle. His leadership and communication will also be vital in ensuring Arizona is lined up properly against Colorado’s fast-paced offense.
Dalton Johnson, S: The Wildcats’ secondary has a standout in Dalton Johnson, a senior safety who has taken on a leadership role. Johnson was one of the players who spoke to the media after the tough loss to Colorado last year, showing his willingness to lead and be accountable. On the field, Dalton Johnson is known for being a hard hitter and an intelligent last line of defense. He often helps get the secondary lined up and will adjust coverages if he sees something. Johnson has also shown a knack for making timely plays – whether it’s an interception, a tipped pass, or a big third-down tackle to force a punt. In the 2025 season, he’s been the stabilizing force for an Arizona defense that has had its ups and downs. His matchup against Colorado will involve a lot of multitasking: sometimes he’ll play deep to prevent the long bomb, other times he’ll creep into the box to help stop the run or blitz. Johnson will need to keep the defense organized, especially against any trickery Colorado might try (Coach Sanders is not afraid to dial up creative plays). One particular challenge will be helping Arizona’s corners cover Colorado’s receivers in that aggressive style – he may have to assist over the top to ensure no Colorado receiver gets behind the defense. If Arizona is to contain Colorado’s offense, Dalton Johnson’s play at safety will be key. Keep an eye out for #1 in the secondary; his effectiveness in reading Colorado’s intentions could lead to a crucial turnover or a momentum-shifting defensive stand.
Taylor Upshaw, DL: In the trenches, a player to note is Taylor Upshaw, a defensive lineman who transferred into Arizona (interestingly, he’s a veteran who actually spent a short stint at Colorado before coming to Arizona). Upshaw provides experience and size up front. He’s been one of Arizona’s better pass rushers and run stoppers in 2025. At around 6-foot-4 and 270 pounds, Upshaw often lines up at defensive end but can move inside on passing downs. His motivation for this game might be extra high given his connection to Colorado’s program. Upshaw will try to generate pressure on Colorado’s quarterback and also set the edge to prevent runs to the outside. If he can win some one-on-one battles against Colorado’s offensive tackles (like the highly touted Jordan Seaton), that could stall the Buffs’ drives. Arizona as a team struggled to sack Colorado’s QB last year (unlike Colorado’s seven-sack performance), so Upshaw and fellow linemen like Orlando Lground or Bill Norton will be determined to change that narrative. Pressure without having to blitz will help Arizona’s defense immensely. Watch for Upshaw on key third downs – if he can flush Salter out of the pocket or bring him down for a sack, it could fire up the Wildcats defense and frustrate Colorado’s offense.

What to Expect from the Matchup

When Colorado and Arizona line up on November 1, expect an intriguing clash of styles and a game full of storylines. Here’s a look at some of the key factors and what to watch for as the game unfolds:

High-Powered Offense vs. Determined Defense: Colorado has built an identity as an explosive offensive team under Coach Prime. They love to spread the field with multiple receivers and let the quarterback air it out. The Buffs “will spread and air the ball out, picking apart secondaries all game long” according to observers of their recent success. So anticipate Colorado to test Arizona’s pass defense early and often. They’ll mix in deep shots downfield with quick screens and slants to playmakers like Drelon Miller. Arizona’s defense, meanwhile, is a unit with a chip on its shoulder. They remember giving up 34 points to these Buffs last year, and they have been focusing on improving their resilience. Defensive coordinator Danny Gonzales (a new addition to the staff known for his aggressive schemes) may dial up blitzes to try to disrupt Colorado’s backfield rhythm. The Wildcats will likely attempt to press Colorado’s receivers at the line to throw off timing, but that carries risk if they get beat. The battle between Colorado’s passing offense and Arizona’s pass defense could decide the game. If Colorado is clicking – moving the ball through the air at will – it could be a long day for Arizona. But if the Wildcats can force a few incompletions, sacks, or turnovers early, they could stall Colorado’s drives and keep the game within reach.
Arizona’s Balance vs. Colorado’s Speed: On the flip side, when Arizona has the ball, they will strive for balance. Coach Brennan has emphasized the need for a balanced attack to avoid obvious passing situations (which hurt them last year, as evidenced by those seven sacks on Fifita). Look for Arizona to establish the run with Jonah Coleman and use short passes as an extension of the run game. The idea will be to sustain drives, chew up some clock, and keep Colorado’s offense on the sideline. Colorado’s defense is built on speed and aggressiveness. Their front seven will try to shoot gaps and swarm to the ball, so Arizona might counter with draws, counters, or screen passes to slow that pursuit. One thing to watch is third-down situations: Arizona will want to stay in third-and-manageable (say, 3rd and 4 or 3rd and 5) where the threat of run or pass keeps Colorado guessing. If instead Arizona often faces 3rd and long, Colorado’s pass rushers like Taje McCoy can tee off and make life difficult for Fifita. The Wildcats likely scripted some quick-release pass plays specifically to avoid a repeat of last year’s protection issues. Fifita getting the ball out fast on slants, hitches, and check-downs could negate Colorado’s speed on defense somewhat. It will be interesting to see if Arizona can impose a more methodical tempo or if Colorado’s defense will force them into a frenetic catch-up mode.
Coaching Chess Match: Both coaching staffs have had this date circled. For Coach Deion Sanders, every conference game is crucial, but he especially wants to hold serve at home and keep momentum. He’s shown a knack for motivating his players to start fast. In fact, last year he challenged his coordinators to get off to better starts, and the team responded with 28 first-half points against Arizona. You can bet Colorado will try to come out with the same urgency and put Arizona in an early hole. Don’t be surprised if Coach Prime has a trick up his sleeve – perhaps a flea-flicker, a reverse, or a fake punt – to capitalize on the home crowd energy and catch Arizona off guard. On the other sideline, Coach Brent Brennan will be looking for any edge he can find. Last year his surprise onside kick to start the game backfired, so he might be a bit more cautious with the trick plays at the very beginning. However, coming off a bye week, Arizona’s staff has had extra time to scout Colorado and maybe install a few new wrinkles. We could see something like a Wildcat formation or a deep shot on an unexpected down from Arizona to try to steal a big play. The coaching chess match also extends to adjustments. If Colorado is having success with something (for example, targeting a specific cornerback), will Arizona adjust their coverage or personnel? If Arizona is running the ball well, will Colorado stack the box or bring an extra defender closer to the line? These in-game adjustments will be pivotal, especially in the second half.
Home Field and Atmosphere: Folsom Field in Boulder can be a tough place for visitors, especially late in the season. The elevation (~5,300 feet above sea level) is always a talking point – Arizona’s players might feel the thin air in the second half, particularly if Colorado pushes the tempo and runs a lot of plays. The Buffs have also been enjoying sold-out crowds ever since Coach Prime came to town. Expect a loud, boisterous atmosphere with Colorado’s fans “buffing up” (in their black and gold) for this night game. On the Arizona side, to simulate the crowd noise and chaos, they likely practiced with loud speakers blasting and emphasized silent snap counts. If Arizona falls behind early, the crowd could become a real factor. Conversely, if Arizona can land a few punches and keep it close or take a lead, you might feel the stadium get a bit anxious – Colorado carries big expectations now, and any sign of struggle might quiet the fans. The first quarter, therefore, is key for Arizona to weather the storm. Every team says they want to start fast, but for the underdog Wildcats it’s especially true: a sustained drive or an early score could settle them in and take the crowd out of it a bit. The environment will also be a test for Coach Brennan’s young quarterback, Noah Fifita. Communication on offense in a noisy road game is challenging; watch for any false start penalties or miscommunications as a sign that the crowd is rattling the Wildcats.
Recent Emotions and Motivation: Emotions will run high in this game. Colorado’s players have a lot of swagger – they play with confidence and will be hyped up in front of their home fans. If they make a big play, expect some celebrating (within the rules, of course). Arizona, on the other hand, comes in hungry and maybe even a little angry. Getting blown out at home last year left a bitter taste. Some Wildcats players probably circled this rematch as soon as the schedules came out. That desire for payback can be a powerful motivator. We might see Arizona come out with extra physicality – maybe a defender lays a big hit early or the offensive linemen try to be especially assertive. It will be important for both teams to keep emotions in check and avoid costly mistakes like unsportsmanlike conduct penalties. The team that can channel the emotional energy into focused play will have the edge. Additionally, both teams have plenty at stake in terms of season goals: Colorado could be in the race for a Big 12 Championship game berth, so they cannot afford a slip-up here. Arizona might be fighting for bowl eligibility, needing every win they can get. With November football, every game’s importance is magnified for postseason aspirations. So expect intensity on every snap – neither side will want to give an inch.
Key Matchup to Watch: One key matchup to highlight is Arizona’s wide receivers vs. Colorado’s cornerbacks. We touched on Tetairoa McMillan versus Carter Stoutmire earlier. That battle could be a thriller: a great receiver against a confident corner, strength on strength. If McMillan wins consistently, Arizona’s passing offense can open up. If Stoutmire shuts him down, Arizona might struggle to move the ball through the air. And if Colorado decides to double-cover McMillan, then how effectively can Arizona’s other receivers win against single coverage? Someone like Kevin Green II or freshman wideout A.J. Jones might need to step up for the Wildcats. Conversely, on the other side, Colorado’s receivers vs. Arizona’s secondary is just as intriguing. Arizona’s defensive backs, led by safety Dalton Johnson, will have their hands full with Colorado’s speed. Will Arizona play zone to try to keep everything in front of them, or will they dare to play man coverage like last year (which did not go well)? The adjustments Arizona makes in their secondary coverage could make a big difference. If you start seeing Colorado receivers running free, it likely means busted coverage or a mismatch exploited. If Arizona manages a couple of pass breakups or an interception, that could be a game-changer.

In terms of the flow of the game, we might see a bit of a chess match early, with both teams probing each other’s defenses. Colorado might take some deep shots early to test Arizona’s corners. Arizona might script some quick passes and runs to see if they can establish the line of scrimmage. By the second quarter, things could open up as adjustments are made. Watch for a potential momentum swing around halftime – either a score before the half or a big play right after. And as we head into the fourth quarter, stamina and depth will play a role. Colorado, having been in some high-stakes games last year, believes it can close games out. Arizona, under a newer regime, is still learning how to finish games strong. If it’s a one-possession game in the fourth, that pressure will be immense on both sides.

Final Thoughts: An Entertaining Big 12 Battle

This Colorado vs. Arizona game has all the ingredients of an entertaining college football showdown. You have a revitalized Colorado program under a charismatic coach playing at home with conference title hopes, and an up-and-coming Arizona team trying to claw its way back to respectability and aiming to upset the apple cart. The contrast in styles – Colorado’s flash and aerial attack vs. Arizona’s attempt at balanced, hard-nosed play – will be fascinating to watch. There’s also the subplot of last year’s blowout giving Arizona plenty of incentive to bring their A-game for redemption.

For the casual fan, expect a good atmosphere and some highlight-worthy plays. Colorado’s squad tends to produce fireworks, whether it’s a long touchdown pass, an acrobatic interception, or even just the energy on the sidelines. Arizona, meanwhile, might impress you with their resilience and the pure effort players like Noah Fifita and Jacob Manu put forward on each down. Even if you’re not deeply familiar with these teams, the narrative is easy to appreciate: it’s about proving oneself. Colorado wants to prove they can be the new bully on the Big 12 block, and Arizona wants to prove they won’t be a bottom-dweller and that last year’s setback was just a stepping stone to a brighter future.

One thing you won’t see is either team giving up — both have very competitive cultures instilled by their coaches. As Coach Sanders has shown, his Buffaloes thrive on doubters and big stages, feeding off energy whether positive or negative. And Coach Brennan’s Wildcats have adopted a workmanlike attitude, emphasizing getting back up when knocked down and continuing to fight. So if the game does get one-sided at any point, don’t expect the trailing team to roll over. A comeback or at least a push to make it close is always possible, especially with the kind of heart these players have shown.

In the end, the outcome could come down to depth and execution. Colorado, playing at home and given their recent track record, will be favored to win – they simply have more momentum coming in. But Arizona is not to be overlooked; they are a dangerous underdog with nothing to lose and a lot to gain. If the Wildcats can avoid early mistakes, capitalize on any Colorado turnovers, and maybe sprinkle in a little magic (think special teams play or trick play success), they could hang around and make this a nail-biter.

No matter what, fans should be informed and entertained by this matchup. It’s a game that highlights what college football is all about: teams adapting to new challenges, young players stepping into big roles, and the unpredictability that makes every Saturday special. So, grab your jersey (be it black and gold or red and navy), settle in, and enjoy the show on November 1, 2025 – the Buffaloes and Wildcats are ready to square off in a battle that will help define their seasons. It’s almost game time in Boulder, and everyone is eager to see how this chapter of Colorado vs. Arizona will be written. Go Buffs and Bear Down – let’s play some football!

Sources:

Colorado and Arizona’s long-standing series history and recent resultswildcat.arizona.edu cubuffs.com
Recap of Colorado’s dominant 34-7 win in 2024 and postgame quotes from both sides azdesertswarm.com ralphiereport.com azdesertswarm.com
Big 12 2024 season context (Colorado’s strong debut, Arizona’s struggles)big12sports.com wildcat.arizona.edu
Notable player information and recruiting news for Colorado (Coach Prime’s recruits and transfers)cubuffs.com cubuffs.com
Arizona player and coach quotes illustrating team mindset and changesazdesertswarm.com azdesertswarm.com
Analysis of Colorado’s strategy and identity under Coach Sanders ralphiereport.com ralphiereport.com